EFFECT OF OVEREXPRESSION OF THE BRAIN-SPECIFIC NA+/CA2+ EXCHANGER SPLICE VARIANT NCX1.5 ON NO CYTOTOXICITY IN HEK293 CELLS

Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

Abstract.: Nitric oxide (NO) induces cytotoxicity in neuronal and glial cells via activation of the Na+/Ca2+ exchanger (NCX).This study examined BEYOND GRAPE SEED the role of the predominant brain-specific NCX splice variant NCX1.5 in NO-induced cytotoxicity in the HEK293 cell expression system.Cells were transfected with the plasmid construct pcDN

read more



Breastfeeding and snoring: a birth cohort study.

OBJECTIVE: To investigate the relationship between breastfeeding and snoring in childhood.METHODS: In a cohort of children with a family history of asthma who were recruited antenatally we prospectively recorded data on infant feeding practices throughout the first year of life.Snoring status and witnessed sleep apnea were measured at age 8 years b

read more